GTX31859
p57 Kip2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31859
- Zusätzliche Namen:
- cyclin dependent kinase inhibitor 1C , BWCR , BWS , KIP2 , WBS , p57 , p57Kip2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- p57 Kip2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human p57 Kip2.The immunogen is located within amino acids 40 - 90 of p57 Kip2.
- Uniprot:
- P49918
- Synonyme:
- BWCR;BWS;cyclin-dependent kinase inhibitor 1C;cyclin-dependent kinase inhibitor 1C (p57, Kip2);cyclin-dependent kinase inhibitor p57;KIP2;p57;p57Kip2;WBS
- Weitere Details:
- This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- Versandbedingungen:
- Blue Ice