GTX31810-PEP
NOD1 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31810-PEP
- Zusätzliche Namen:
- Nucleotide Binding Oligomerization Domain Containing 1 , Card4 , Clr7.1 , Nlrc1 , Nod1
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- nucleotide binding oligomerization domain containing 1
- Spezies:
- Human
- Synonyme:
- CARD4;caspase recruitment domain family, member 4;caspase recruitment domain-containing protein 4;CLR7.1;NLR family, CARD domain containing 1;NLRC1;nucleotide-binding oligomerization domain-containing protein 1;nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
- Weitere Details:
- This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009]
- Versandbedingungen:
- Dry Ice