NABC1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX31800
Zusätzliche Namen:: breast carcinoma amplified sequence 1 , AIBC1 , NABC1
Anwendung:: ELISA, WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: NABC1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human NABC1 .The immunogen is located within amino acids 460 - 510 of NABC1 .
Uniprot:: O75363
Synonyme:: AIBC1;amplified and overexpressed in breast cancer;breast carcinoma amplified sequence 1;breast carcinoma-amplified sequence 1;NABC1;novel amplified in breast cancer 1;PMES-2;protein having mRNA enriched in synaptosomes 2
Weitere Details:: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]