GTX31758
BUB1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31758
- Zusätzliche Namen:
- BUB1 mitotic checkpoint serine/threonine kinase , BUB1A , BUB1L , hBUB1
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Bub1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Bub1.The immunogen is located within amino acids 40 - 90 of Bub1.
- Uniprot:
- O43683
- Synonyme:
- BUB1 budding uninhibited by benzimidazoles 1 homolog;BUB1A;BUB1L;budding uninhibited by benzimidazoles 1 homolog;hBUB1;mitotic checkpoint serine/threonine-protein kinase BUB1;mitotic spindle checkpoint kinase;putative serine/threonine-protein kinase
- Weitere Details:
- This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Versandbedingungen:
- Blue Ice