STIM1 blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX31757-PEP
Zusätzliche Namen:: Stromal Interaction Molecule 1 , D11S4896E , Gok , Imd10 , Strmk , Tam , Tam1 , Stim1
Anwendung:: Neutralisation
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: stromal interaction molecule 1
Spezies:: Human
Synonyme:: D11S4896E;GOK;IMD10;STRMK;stromal interaction molecule 1;TAM;TAM1
Weitere Details:: This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.[provided by RefSeq, Jan 2009]