GTX31740
TANK antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31740
- Zusätzliche Namen:
- TRAF family member associated NFKB activator , I-TRAF , ITRAF , TRAF2
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TANK antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TANK.The immunogen is located within amino acids 350 - 400 of TANK.
- Uniprot:
- Q92844
- Synonyme:
- I-TRAF;ITRAF;TRAF family member-associated NF-kappa-B activator;TRAF-interacting protein;TRAF2
- Weitere Details:
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
- Versandbedingungen:
- Blue Ice