GTX31701-PEP
Caspase 5 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31701-PEP
- Zusätzliche Namen:
- Caspase 5 , Ice(Rel)Iii , Icerel-Iii , Ich-3 , Casp5
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- caspase 5
- Spezies:
- Human
- Synonyme:
- caspase 5 variant X1;caspase 5, apoptosis-related cysteine peptidase;caspase 5, apoptosis-related cysteine protease;caspase-5;ICE(rel)III;ICEREL-III;ICH-3;protease ICH-3;protease TY;TY protease
- Weitere Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
- Versandbedingungen:
- Dry Ice