GTX31693-PEP
TAB3 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31693-PEP
- Zusätzliche Namen:
- Tgf-Beta Activated Kinase 1 (Map3K7) Binding Protein 3 , Map3K7Ip3 , Nap1 , Tab3
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- TGF-beta activated kinase 1/MAP3K7 binding protein 3
- Spezies:
- Human
- Synonyme:
- MAP3K7IP3;mitogen-activated protein kinase kinase kinase 7 interacting protein 3;NAP1;NF-kappa-B-activating protein 1;NFkB activating protein 1;TAB-3;TAK1-binding protein 3;TGF-beta activated kinase 1 and MAP3K7 binding protein 3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;TGF-beta-activated kinase 1-binding protein 3
- Weitere Details:
- The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Dry Ice