GTX31688
Bad antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31688
- Zusätzliche Namen:
- BCL2 associated agonist of cell death , BBC2 , BCL2L8
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ion Exchange
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.The immunogen is located within amino acids 90 - 140 of BAD.
- Uniprot:
- Q92934
- Synonyme:
- BBC2;bcl-2-binding component 6;bcl-2-like protein 8;BCL-X/BCL-2 binding protein;bcl-XL/Bcl-2-associated death promoter;bcl2 antagonist of cell death;BCL2-antagonist of cell death protein;bcl2-associated agonist of cell death;BCL2-binding component 6;BCL2-binding protein;bcl2-L-8;BCL2L8
- Weitere Details:
- The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice