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GTX31619-PEP

ARID1A blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX31619-PEP
Zusätzliche Namen:
At-Rich Interaction Domain 1A , B120 , Baf250 , Baf250A , Bm029 , C1Orf4 , Css2 , Eld , Mrd14 , Osa1 , P270 , Smarcf1 , Held , Hosa1 , Arid1A
Anwendung:
Neutralisation
Konzentration:
200 ug/ml
Physischer Zustand:
Liquid
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Hersteller:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
AT-rich interaction domain 1A
Spezies:
Human
Synonyme:
ARID domain-containing protein 1A;AT rich interactive domain 1A (SWI-like);AT-rich interactive domain-containing protein 1A;B120;BAF250;BAF250a;BM029;brain protein 120;BRG1-associated factor 250a;C1orf4;chromatin remodeling factor p250;CSS2;ELD;hELD;hOSA1;MRD14;osa homolog 1;OSA1;OSA1 nuclear protein;P270;SMARCF1;SWI-like protein;SWI/SNF complex protein p270;SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1
Weitere Details:
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isof
Versandbedingungen:
Dry Ice