GTX31529
KREMEN2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31529
- Zusätzliche Namen:
- kringle containing transmembrane protein 2 , KRM2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 .The immunogen is located within amino acids 390 - 440 of KREMEN2.
- Uniprot:
- Q8NCW0
- Synonyme:
- dickkopf receptor 2;kremen protein 2;kringle domain-containing transmembrane protein 2;kringle-containing protein marking the eye and the nose;KRM2
- Weitere Details:
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Versandbedingungen:
- Blue Ice