SHANK3 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX31480
Zusätzliche Namen:: SH3 and multiple ankyrin repeat domains 3 , DEL22q13.3 , PROSAP2 , PSAP2 , SCZD15 , SPANK-2
Anwendung:: ELISA, WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: SHANK3 antibody was raised against a 19 amino acid synthetic peptide near the center of human SHANK3.The immunogen is located within amino acids 890 - 940 of SHANK3.
Uniprot:: Q9BYB0
Synonyme:: DEL22q13.3;proline rich synapse associated protein 2;Proline-rich synapse-associated protein 2;PROSAP2;PSAP2;SCZD15;SH3 and multiple ankyrin repeat domains protein 3;shank postsynaptic density protein;shank3 postsynaptic density protein;SPANK-2
Weitere Details:: This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]

Versandbedingungen:: Blue Ice