GTX31469
GRB10 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31469
- Zusätzliche Namen:
- growth factor receptor bound protein 10 , GRB-IR , Grb-10 , IRBP , MEG1 , RSS
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.The immunogen is located within amino acids 440 - 490 of GRB10.
- Uniprot:
- Q13322
- Synonyme:
- Grb-10;GRB-IR;GRB10 adapter protein;GRB10 adaptor protein;growth factor receptor-bound protein 10;insulin receptor-binding protein Grb-IR;IRBP;maternally expressed gene 1;MEG1;RSS
- Weitere Details:
- The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
- Versandbedingungen:
- Blue Ice