GTX31440
Translin antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31440
- Zusätzliche Namen:
- translin , BCLF-1 , C3PO , RCHF1 , REHF-1 , TBRBP , TRSLN
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.The immunogen is located within the last 50 amino acids of Translin.
- Uniprot:
- Q15631
- Synonyme:
- BCLF-1;C3PO;component 3 of promoter of RISC;RCHF1;recombination hotspot associated factor;recombination hotspot-binding protein;REHF-1;TBRBP;testis brain-RNA binding protein;translin;TRSLN
- Weitere Details:
- This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
- Versandbedingungen:
- Blue Ice