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GTX31440-PEP

Translin blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX31440-PEP
Zusätzliche Namen:
Translin , Bclf-1 , C3Po , Rchf1 , Rehf-1 , Tbrbp , Trsln , Tsn
Anwendung:
Neutralisation
Konzentration:
200 ug/ml
Physischer Zustand:
Liquid
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Hersteller:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
translin
Spezies:
Human
Synonyme:
BCLF-1;C3PO;component 3 of promoter of RISC;RCHF1;recombination hotspot associated factor;recombination hotspot-binding protein;REHF-1;TBRBP;testis brain-RNA binding protein;translin;TRSLN
Weitere Details:
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Versandbedingungen:
Dry Ice