GTX31438
IRF4 / MUM1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31438
- Zusätzliche Namen:
- interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- IRF4 / MUM1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human IRF4 / MUM1.The immunogen is located within the last 50 amino acids of IRF4 / MUM1.
- Uniprot:
- Q15306
- Synonyme:
- interferon regulatory factor 4;LSIRF;lymphocyte-specific interferon regulatory factor;multiple myeloma oncogene 1;MUM1;NF-EM5;SHEP8
- Weitere Details:
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
- Versandbedingungen:
- Blue Ice