GTX31411
PIAS2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31411
- Zusätzliche Namen:
- protein inhibitor of activated STAT 2 , ARIP3 , DIP , MIZ1 , PIASX , SIZ2 , ZMIZ4
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PIAS2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human PIAS2.The immunogen is located within amino acids 110 - 160 of PIAS2.
- Uniprot:
- O75928
- Synonyme:
- androgen receptor-interacting protein 3;ARIP3;DAB2-interacting protein;DIP;E3 SUMO-protein ligase PIAS2;E3 SUMO-protein transferase PIAS2;MIZ1;msx-interacting zinc finger protein;PIAS-NY protein;PIASX;protein inhibitor of activated STAT X;Protein inhibitor of activated STAT2;SIZ2;zinc finger, MIZ-type containing 4;ZMIZ4
- Weitere Details:
- This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice