GTX31410
PIAS1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31410
- Zusätzliche Namen:
- protein inhibitor of activated STAT 1 , DDXBP1 , GBP , GU/RH-II , ZMIZ3
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PIAS1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PIAS1.The immunogen is located within the last 50 amino acids of PIAS1.
- Uniprot:
- O75925
- Synonyme:
- AR interacting protein;DDXBP1;DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1;DEAD/H box-binding protein 1;E3 SUMO-protein ligase PIAS1;E3 SUMO-protein transferase PIAS1;GBP;gu-binding protein;GU/RH-II;protein inhibitor of activated STAT protein 1;RNA helicase II-binding protein;zinc finger, MIZ-type containing 3;ZMIZ3
- Weitere Details:
- This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice