GTX31366
GLE1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31366
- Zusätzliche Namen:
- GLE1 RNA export mediator , CAAHC , CAAHD , GLE1L , LCCS , LCCS1 , hGLE1
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Gle1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1.The immunogen is located within amino acids 540 - 590 of Gle1.
- Uniprot:
- Q53GS7
- Synonyme:
- CAAHC;CAAHD;GLE1 RNA export mediator homolog;GLE1-like protein;GLE1-like, RNA export mediator;GLE1L;hGLE1;LCCS;LCCS1;nucleoporin GLE1
- Weitere Details:
- This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice