GTX31361
OTUD5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31361
- Zusätzliche Namen:
- OTU deubiquitinase 5 , DUBA
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- OTUD5 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human OTUD5.The immunogen is located within amino acids 400 - 450 of OTUD5.
- Uniprot:
- Q96G74
- Synonyme:
- deubiquinating enzyme A;deubiquitinating enzyme A;DUBA;MCAND;OTU domain containing 5;OTU domain-containing protein 5
- Weitere Details:
- This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
- Versandbedingungen:
- Blue Ice