![TREM2 antibody [78.18]](https://www.genetex.com/upload/website/prouct_img/normal/GTX31235/GTX31235_5628_FACS_w_23051500_497.webp)
GTX31235
TREM2 antibody [78.18]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31235
- Zusätzliche Namen:
- triggering receptor expressed on myeloid cells 2 , TREM-2 , Trem2a , Trem2b , Trem2c
- Anwendung:
- Flow Cytometry
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- Mouse TREM-2 Fc fusion protein.
- Klon:
- 78.18
- Uniprot:
- Q99NH8
- Synonyme:
- Trem;TREM-2;Trem2a;Trem2b;Trem2c;triggering receptor expressed on monocytes 2;triggering receptor expressed on myeloid cells 2;triggering receptor expressed on myeloid cells 2a;triggering receptor expressed on myeloid cells 2b;triggering receptor expressed on myeloid cells 2c
- Weitere Details:
- The protein encoded by this gene is part of the immunoglobulin and lectin-like superfamily and functions as part of the innate immune system. This gene forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. This protein associates with the adaptor protein Dap-12 and recruits several factors, such as kinases and phospholipase C-gamma, to form a receptor signaling complex that activates myeloid cells, including dendritic cells and microglia. In humans homozygous loss-of-function mutations in this gene cause Nasu-Hakola disease and mutations in this gene may be risk factors to the development of Alzheimer's disease. In mouse mutations of this gene serve as a pathophysiological model for polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease) and for inflammatory bowel disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]
- Versandbedingungen:
- Blue Ice