GTX31056
mGluR2 + mGluR3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31056
- Anwendung:
- ELISA, IHC, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- Synthetic peptide, corresponding to amino acids 836-872 of Human mGluR-2.
- Weitere Details:
- The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-2, which may interact with GRASP, acts as a receptor for glutamate. It may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stablization. mGluR-3,which may interact with GRASP, acts as a receptor for glutamate.
- Versandbedingungen:
- Blue Ice