GTX31003
GABA A Receptor alpha 4 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31003
- Zusätzliche Namen:
- gamma-aminobutyric acid type A receptor alpha4 subunit
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-EKAKRKTSKPPQE, from the internal region of the protein sequence according to NP_000800.2.
- Uniprot:
- P48169
- Synonyme:
- GABA(A) receptor subunit alpha-4;GABA(A) receptor, alpha 4;gamma-aminobutyric acid (GABA) A receptor, alpha 4;gamma-aminobutyric acid A receptor alpha 4;gamma-aminobutyric acid receptor subunit alpha-4;gamma-aminobutyric acid type A receptor alpha4 subunit
- Weitere Details:
- Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
- Versandbedingungen:
- Blue Ice