GTX30689
NUMB antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX30689
- Zusätzliche Namen:
- NUMB endocytic adaptor protein , Nb
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 3.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
- Immunogen:
- A synthetic peptide made to a C-terminal region of mouse NUMB (between residues 600-653). [UniProt# Q9QZS3]
- Uniprot:
- Q9QZS3
- Synonyme:
- m-num;Nb;numb gene homolog;numb homolog;protein numb homolog
- Weitere Details:
- Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
- Versandbedingungen:
- Blue Ice