GTX30646
HIF1AN antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX30646
- Zusätzliche Namen:
- hypoxia inducible factor 1 subunit alpha inhibitor , FIH1
- Anwendung:
- IHC, WB, IHC-P, IHC-Fr, IF, ICC, IP, EM
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Tris-Citrate/Phosphate, 0.1% Sodium azide.
- Immunogen:
- A synthetic peptide made to the C-terminal region of human Factor Inhibiting HIF-1 (between residues 300 and the C-terminus). [UniProt# Q9NWT6]
- Uniprot:
- Q9NWT6
- Synonyme:
- factor inhibiting HIF-1;factor inhibiting HIF1;FIH-1;FIH1;hypoxia inducible factor 1 alpha subunit inhibitor;hypoxia-inducible factor 1-alpha inhibitor;hypoxia-inducible factor asparagine hydroxylase;peptide-aspartate beta-dioxygenase
- Weitere Details:
- Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
- Versandbedingungen:
- Blue Ice