TERT antibody [2C4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX30410
Zusätzliche Namen:: telomerase reverse transcriptase , CMM9 , DKCA2 , DKCB4 , EST2 , PFBMFT1 , TCS1 , TP2 , TRT , hEST2 , hTRT
Anwendung:: ChIP, Flow Cytometry, WB, IHC-P, IF, ICC, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Full-length recombinant human Telomerase reverse transcriptase from insect cells. [UniProt# O14746].
Klon:: 2C4
Uniprot:: O14746
Synonyme:: CMM9;DKCA2;DKCB4;EST2;hEST2;hTRT;PFBMFT1;TCS1;telomerase catalytic subunit;telomerase reverse transcriptase;telomerase-associated protein 2;TP2;TRT
Weitere Details:: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq]

Versandbedingungen:: Blue Ice