GTX30114
HIF2 alpha antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX30114
- Zusätzliche Namen:
- endothelial PAS domain protein 1 , HIF-2alpha , HIF2A , HLF , HRF , MOP2 , bHLHe73
- Anwendung:
- IHC, WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Fish, Human, Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- A peptide derived from the mouse/human HIF2 alpha.
- Uniprot:
- P97481
- Synonyme:
- bHLHe7;bHLHe73;endothelial PAS domain-containing protein 1;EPAS-1;HIF;Hif like protein;HIF-1-alpha-like factor;HIF-2;HIF-2-alpha;HIF-2alpha;HIF-related factor;HIF1 alpha-like factor;HIF1alpha-like factor;HIF2-alpha;HIF2A;HL;HLF;HLF (HIF1alpha-like factor);HR;HRF;hypoxia inducible transcription factor 2alpha;hypoxia-inducible factor 2-alpha;mHLF;MO;MOP2
- Weitere Details:
- Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells. (1)
- Versandbedingungen:
- Blue Ice