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  1. Alles ansehen
  2. Polyclonal

GTX30077

ATP7b antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX30077
Zusätzliche Namen:
ATPase copper transporting beta , PWD , WC1 , WD , WND
Anwendung:
WB, IF, ICC
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1055-1354 of human ATP7B (NP_001230111.1).
Uniprot:
P35670
Synonyme:
ATPase, Cu(2+)- transporting, beta polypeptide;ATPase, Cu++ transporting, beta polypeptide;copper pump 2;copper-transporting ATPase 2;copper-transporting protein ATP7B;PWD;WC1;WD;Wilson disease-associated protein;WND
Weitere Details:
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice