GTX29645
PUMA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX29645
- Zusätzliche Namen:
- BBC3 , BCL2 binding component 3 , JFY1 , PUMA
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to aa 2-16 of human PUMA-A Alpha (accession no. NP_055232).. This sequence is identical in mouse PUMA-A Alpha.
- Uniprot:
- Q96PG8, Q9BXH1
- Synonyme:
- bcl-2-binding component 3;JFY-1;JFY1;p53 up-regulated modulator of apoptosis;p53-upregulated modulator of apoptosis;PUMA
- Weitere Details:
- This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
- Versandbedingungen:
- Blue Ice