GTX29526
NHERF1 antibody [EBP-10]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX29526
- Zusätzliche Namen:
- EBP50 , NHERF , NHERF1 , NPHLOP2 , SLC9A3 regulator 1 , SLC9A3R1 , NHE-RF1
- Anwendung:
- WB, IHC-P, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- Bacterially produced recombinant full-length human NHERF1.
- Klon:
- EBP-10
- Uniprot:
- O14745
- Synonyme:
- EBP50;ezrin-radixin-moesin binding phosphoprotein-50;Ezrin-radixin-moesin-binding phosphoprotein 50;Na(+)/H(+) exchange regulatory cofactor NHE-RF1;Na+/H+ exchange regulatory co-factor;NHERF;NHERF-1;NHERF1;NPHLOP2;regulatory cofactor of Na(+)/H(+) exchanger;Sodium-hydrogen exchanger regulatory factor 1;Solute carrier family 9 isoform A3 regulatory factor 1;solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
- Weitere Details:
- This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
- Versandbedingungen:
- Blue Ice