GTX28464
RIP3 peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX28464
- Zusätzliche Namen:
- Receptor-Interacting Serine-Threonine Kinase 3 , 2610528K09Rik , Aw107945 , Rip3 , Ripk3
- Anwendung:
- Neutralisation
- Konzentration:
- 0.20 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- receptor-interacting serine-threonine kinase 3
- Spezies:
- Mouse
- Synonyme:
- 2610528K09Rik;AW107945;mRIP3;R;receptor interacting protein 3;receptor-interacting serine/threonine-protein kinase 3;RIP-3;RIP-like protein kinase 3;Rip3
- Weitere Details:
- Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Over expression of RIP3 induces apoptosis and NF-kB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.
- Versandbedingungen:
- Dry Ice