GTX28454
DRAK2 peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX28454
- Zusätzliche Namen:
- Serine/Threonine Kinase 17B , Drak2 , Stk17B
- Anwendung:
- Neutralisation
- Konzentration:
- 0.20 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- serine/threonine kinase 17b
- Spezies:
- Human
- Synonyme:
- DAP kinase-related apoptosis-inducing protein kinase 2;death-associated protein kinase-related 2;DRAK2;serine/threonine-protein kinase 17B
- Weitere Details:
- Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
- Versandbedingungen:
- Dry Ice