GTX28426
RAIDD antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX28426
- Zusätzliche Namen:
- CASP2 and RIPK1 domain containing adaptor with death domain , CRADD , MRT34 , RAIDD
- Anwendung:
- ELISA, WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 99- 117 of human RAIDD (accession no. AAB42217).
- Uniprot:
- P78560
- Synonyme:
- Caspase and RIP adapter with death domain;caspase and RIP adaptor with death domain;CRADD/LYZ fusion;death adaptor molecule RAIDD;death domain containing protein CRADD;death domain-containing protein CRADD;MRT34;RAIDD;RIP-associated ICH1/CED3-homologous protein with death domain;RIP-associated protein with a death domain
- Weitere Details:
- This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
- Versandbedingungen:
- Blue Ice