CXCR6 peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX28388
Zusätzliche Namen:: C-X-C Motif Chemokine Receptor 6 , Bonzo , Cd186 , Strl33 , Tymstr , Cxcr6
Anwendung:: Neutralisation
Konzentration:: 0.20 mg/ml
Physischer Zustand:: Liquid
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: chemokine (C-X-C motif) receptor 6
Spezies:: Human
Synonyme:: BONZO;C-X-C chemokine receptor type 6;CD186;CDw186;chemokine (C-X-C motif) receptor 6;G protein-coupled receptor;G-protein coupled receptor bonzo;G-protein coupled receptor STRL33;STRL33;TYMSTR
Weitere Details:: Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T-cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV-1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.