TNF alpha antibody [2C8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX28348
Zusätzliche Namen:: tumor necrosis factor , DIF , TNF-alpha , TNFA , TNFSF2 , TNLG1F
Anwendung:: ELISA, IHC, Neutralisation
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Human recombinant tumor necrosis factor of alpha type.
Klon:: 2C8
Uniprot:: P01375
Synonyme:: APC1 protein;Cachectin;DIF;TNF-a;TNF-alpha;TNF, macrophage-derived;TNF, monocyte-derived;TNFA;TNFSF2;TNLG1F;tumor necrosis factor;tumor necrosis factor ligand 1F;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha
Weitere Details:: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]