GTX28346
PAPP A antibody [10E1]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX28346
- Zusätzliche Namen:
- pappalysin 1 , ASBABP2 , DIPLA1 , IGFBP-4ase , PAPA , PAPP-A , PAPPA1
- Anwendung:
- ELISA, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- Purified human PAPP-A antigen.
- Klon:
- 100
- Uniprot:
- Q13219
- Synonyme:
- ASBABP2;aspecific BCL2 ARE-binding protein 2;differentially placenta 1 expressed protein;DIPLA1;IGF-dependent IGFBP-4 protease;IGFBP-4ase;insulin-like growth factor-dependent IGF binding protein-4 protease;Insulin-like growth factor-dependent IGF-binding protein 4 protease;PAPA;PAPP-A;PAPPA1;pappalysin-1;Pregnancy-associated plasma protein A;pregnancy-associated plasma protein A, pappalysin 1
- Weitere Details:
- This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice