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  2. Polyclonal

GTX28132

Neurofibromin antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX28132
Zusätzliche Namen:
neurofibromin 1 , NFNS , VRNF , WSS
Anwendung:
WB, IHC-P, IHC-Fr, IF, ICC
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Unpurified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Serum, 0.02% Sodium azide.
Immunogen:
An N-terminal peptide of Neurofibromin 1 (within amino acids 1-50). [UniProt# P21359]
Uniprot:
P21359
Synonyme:
neurofibromatosis 1;neurofibromatosis-related protein NF-1;neurofibromin;NFNS;truncated neurofibromin 1;VRNF;WSS
Weitere Details:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq]
Versandbedingungen:
Blue Ice