GTX28105
p53R2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX28105
- Zusätzliche Namen:
- MTDPS8A , MTDPS8B , P53R2 , RRM2B , ribonucleotide reductase regulatory TP53 inducible subunit M2B , p53R2
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 2-17 of human p53R2.
- Uniprot:
- Q7LG56
- Synonyme:
- MTDPS8A;MTDPS8B;p53-inducible ribonucleotide reductase small subunit 2 homolog;p53-inducible ribonucleotide reductase small subunit 2 short form beta;p53-inducible ribonucleotide reductase small subunit 2-like protein;P53R2;ribonucleoside-diphosphate reductase subunit M2 B;ribonucleotide reductase M2 B (TP53 inducible);TP53-inducible ribonucleotide reductase M2 B
- Weitere Details:
- This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
- Versandbedingungen:
- Blue Ice