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GTX27761

C-Peptide antibody [C-PEP-01]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX27761
Zusätzliche Namen:
insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Anwendung:
ELISA, RIA, IHC-P, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Purified
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
Human C-peptide conjugated to bovine serum albumin.
Klon:
C-PEP-01
Uniprot:
P01308
Synonyme:
IDDM;IDDM1;IDDM2;ILPR;insulin;IRDN;MODY10;PNDM4;preproinsulin;proinsulin
Weitere Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Versandbedingungen:
Blue Ice