GTX27748
IL1 Receptor 2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX27748
- Anwendung:
- ELISA
- Konzentration:
- 0.1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Weitere Details:
- The IL-1 system includes two agonists (IL-1a and IL-1b), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. The IL-1 RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signaling IL-1 RI. The decoy IL-1 RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by co-receptor competition. Further a soluble form of IL-1 RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
- Versandbedingungen:
- Blue Ice