GTX27540
CREB antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX27540
- Zusätzliche Namen:
- cAMP responsive element binding protein 1 , CREB , CREB-1
- Anwendung:
- ChIP, ELISA, WB
- Konzentration:
- 2.56 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- CREB-1 (p43) peptide corresponding to a region near the N-terminus of the human protein, conjugated to KLH.
- Uniprot:
- P16220
- Synonyme:
- active transcription factor CREB;cAMP-response element-binding protein-1;CREB;CREB-1;cyclic adenosine 3',5'-monophosphate response element binding protein;cyclic adenosine 3',5'-monophosphate response element-binding protein CREB;cyclic AMP-responsive element-binding protein 1;transactivator protein
- Weitere Details:
- cyclic AMP responsive element binding protein (CREB) is a ubiquitous transcription factor regulated by changes in cyclic AMP (cAMP) levels. CREB binds as a homodimer to CRE sites (cAMP response elements) and belongs to the basic leucine zipper family of DNA binding proteins. Increases in cAMP levels result in the specific phosphorylation of CREB by protein kinase A. Phosphorylated CREB interacts with the transcriptional co-activator CBP (CREB binding protein or p265). It has recently been demonstrated that CREB phosphorylation correlates with light regulated circadian rhythms.
- Versandbedingungen:
- Blue Ice