GTX27355
Acinus antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX27355
- Zusätzliche Namen:
- ACIN1 , ACINUS , ACN , apoptotic chromatin condensation inducer 1 , fSAP152 , Acinus
- Anwendung:
- ELISA, WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 994- 1009 of human AcinusL, aa 236-251 of human Acinus S and aa 267-282 of human AcinusS' which are identical to those of mouse Acinus. These sequences are located near the N-terminus of active peptide p17.
- Uniprot:
- Q9UKV3
- Synonyme:
- ACINUS;ACN;apoptotic chromatin condensation inducer in the nucleus;fSAP152;functional spliceosome-associated protein 152
- Weitere Details:
- Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice