GTX26586
Collagen IV antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX26586
- Zusätzliche Namen:
- collagen type IV alpha 1 chain , BSVD , RATOR
- Anwendung:
- WB, IHC-P, IF, ICC, IP, Dot blot
- Konzentration:
- 1.17 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Bovine, Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Collagen Type IV from human and bovine placenta
- Uniprot:
- P02462
- Synonyme:
- arresten;BSVD;BSVD1;COL4A1 NC1 domain;COL4A1s;collagen alpha-1(IV) chain;collagen IV, alpha-1 polypeptide;collagen of basement membrane, alpha-1 chain;PADMAL;RATOR
- Weitere Details:
- This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix, which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
- Versandbedingungen:
- Blue Ice