GTX26087
BCMA Peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX26087
- Zusätzliche Namen:
- Tnf Receptor Superfamily Member 17 , Bcm , Bcma , Cd269 , Tnfrsf13A , Tnfrsf17
- Anwendung:
- Neutralisation
- Konzentration:
- 0.20 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Spezies:
- Human
- Synonyme:
- B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17
- Weitere Details:
- Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
- Versandbedingungen:
- Dry Ice