GTX26037
PDZK3 antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX26037
- Zusätzliche Namen:
- AIPC,PAPIN,PDZ domain containing 2,PDZD2,PDZK3,PIN1
- Anwendung:
- IHC-P, IF, ICC
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence PITQDNAVLHLPLC, from the N Terminus of the protein sequence according to NP_835260.2.
- Uniprot:
- O15018
- Synonyme:
- activated in prostate cancer protein;AIPC;PAPIN;PDZ domain-containing protein 2;PDZ domain-containing protein 3;PDZK3;PIN1;plakophilin-related armadillo repeat protein-interactive PDZ protein
- Weitere Details:
- Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice