GTX25965
BAFF Receptor antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX25965
- Zusätzliche Namen:
- BAFFR , BROMIX , CD268 , CVID4 , TNF receptor superfamily member 13C , TNFRSF13C , prolixin , BAFF Receptor
- Anwendung:
- IHC, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 169-183 at the C-terminus of human BAFF-R.
- Uniprot:
- Q96RJ3
- Synonyme:
- B cell-activating factor receptor;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BAFFR;BLyS receptor 3;BROMIX;CD268;CVID4;prolixin;tumor necrosis factor receptor superfamily member 13C
- Weitere Details:
- B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice