GTX25941-PEP
Syntrophin alpha 1 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX25941-PEP
- Zusätzliche Namen:
- Syntrophin Alpha 1 , Lqt12 , Snt1 , Tacip1 , Dj1187J4.5 , Snta1
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- syntrophin alpha 1
- Spezies:
- Human
- Synonyme:
- 59 kDa dystrophin-associated protein A1 acidic component 1;acidic alpha 1 syntrophin;alpha-1-syntrophin;dJ1187J4.5;dystrophin-associated protein A1, 59kDa, acidic component;LQT12;pro-TGF-alpha cytoplasmic domain-interacting protein 1;SNT1;syntrophin-1;TACIP1
- Weitere Details:
- Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
- Versandbedingungen:
- Blue Ice