GTX25497
IGF1R beta antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX25497
- Zusätzliche Namen:
- insulin like growth factor 1 receptor , IGFR , CD221 , IGFIR , JTK13 , IGF1R
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Dialysis
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).
- Uniprot:
- P08069
- Synonyme:
- CD221;IGF-I receptor;IGFIR;IGFR;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Weitere Details:
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Versandbedingungen:
- Blue Ice