GTX23834
Artemis antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX23834
- Zusätzliche Namen:
- DNA cross-link repair 1C , A-SCID , DCLREC1C , RS-SCID , SCIDA , SNM1C
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).
- Uniprot:
- Q96SD1
- Synonyme:
- A-SCID;DCLREC1C;DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae);DNA cross-link repair 1C protein;Protein A-SCID;protein artemis;RS-SCID;SCIDA;severe combined immunodeficiency, type a (Athabascan);SNM1 homolog C;SNM1-like protein;SNM1C
- Weitere Details:
- Human Artemis, a new identified 78.4 KD, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
- Versandbedingungen:
- Blue Ice