GTX23629
Apc10 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX23629
- Zusätzliche Namen:
- anaphase promoting complex subunit 10 , APC10 , DOC1
- Anwendung:
- ELISA, IHC, WB, IP
- Konzentration:
- 1.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
- Uniprot:
- Q9UM13
- Synonyme:
- anaphase-promoting complex subunit 10;APC10;cyclosome subunit 10;DOC1
- Weitere Details:
- APC is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds 1/Cut 2 and cyclin B. It was found that APC 10/Doc 1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid body in telophase and cytokinesis. These results strongly support the notion that human APC 10/Doc 1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
- Versandbedingungen:
- Blue Ice